Stroke Know the signs
 
 
 
 

Subarachnoid Haemorrhage

KNOW THE SIGNS, PREVENT DEATH AND DISABILITY

Subarachnoid haemorrhage (SAH) is a subtype of stroke. It is classified as an haemorrhagic stroke and occurs in about 5% of cases of stroke. The other significant haemorrhagic stroke subtype is the spontaneous intracerebral haemorrhage (ICH) which is found in approximately 15% of cases.

The annual incidence of SAH varies in many populations with smaller incidence in India and the recorded highest incidence in Finland (up to 20/100,000). We have previously reported that unavailability of CT scans may impact on the incidence figures in developing countries.

Patients with SAH present in three ways mainly. The first is with prodromal symptoms of an impending rupture. This has been called the sentinel or warning leak. Typically, over half of the patients with SAH have some preceeding headache or constitutional signs of ill-health. This is often ignored by both patients and more worrying, doctors. The second phase is the catastrophic SAH which cannot be ignored by the patient and associated with severe headache and varying levels of loss of consciousness. Finally, some patients present with delayed effects of vasospasm or rebleeding.

The key solution to the problem of SAH is in the early identification of the aneurysm before it ruptures and effective surgical or endovascular treatment. For too long, doctors have made mistakes in the assessment of patients presenting with unusual headaches- unusual for the patient. The classical history has been misdiagnosed as migraine in some cases with fatal consequences for the patient.

Subarachnoid haemorrhage is a devastating illness which affects mostly women around the age of 50 years. Over the decades the treatment of patients with SAH has improved with better diagnosis and definitive therapy. Long-term trends indicate that the mortality of SAH may be decreasing. Falling incidence rates have been postulated though others believe that better medical practice and standard of care is likely to be a major factor. The improvements in microsurgical, endovascular techniques and general medical management of the acutely ill patient, has to a large extent appeared to improve the outcome for our patients.

In reality, the morbidity and mortality has not really changed from the days of Wylie McKissock and others. Pakarinen and other found that on average 40-50% of patients die without getting to the hospital and of the survivors, a third will die, a third become disabled and a third achieve good outcome. Surgery and endovascular therapy have made a significant and visible impact in good grade patients but overall, the morbidity and mortality is related to the effects of the initial haemorrhage and brain damage, vasospasm and rebleeding. Subarachnoid haemorrhage is a devastating illness and the mortality has not changed dramatically over the years.

 
     
 

Management:

 
  The history of the onset of sudden severe headache is common and remains classical. Patients are carefully reviewed for neck stiffness, photophobia, level of consciousness and focal neurological deficit. The diagnosis is confirmed by either CT or lumbar puncture for CSF analysis. In patients with a classical history and evidence of SAH (CT or LP) we usually proceed to angiography if the patient is well enough for the procedure.  
 
Grade 2 SAH
 
     
  Clinical grade at admission: The World Federation of Neurological Surgeons Scale (WFNS) is used to determine clinical grade at admission and Glasgow Outcome Scale (GOS) for evaluation of outcome at discharge and at six months.  
     
     
 

Outcome:

 
  Many reports detail the value of endovascular treatment of aneurysms and the favorable short-term outcome. Endovascular therapy does not fare better than surgery and the short-term results are comparable. The recent ISAT communications indicate that the results of endovascular therapy are better than surgery at one year of follow-up. Longer outcome results are yet to be determined. Previous reports have detailed the efficacy of embolisation of different aneurysms  
     
 
Unruptured Acutely ruptured Giant Multiple aneurysms Basilar
Unruptured
Acutely ruptured
Giant
Giant
Basilar
     
  also posterior circulation and those in poor grade patients. Subarachnoid haemorrhage is a devastating illness and the mortality has not changed dramatically over the years. Up to 50% of patients die or are disabled by the severity of the illness. Of those that present alive to a competent hospital, only approximately 50% are able to return home alive and 'well'.  
 

 

The major causes of death in patients with SAH are

  • Direct effect of raised intracranial pressure with herniation and brain stem compression
  • Effect of an intracerebral haemorrhage
  • Hydrocephalus
  • Severe vasospasm causing cerebral ischemia
  • Rebleeding
  • Complications of medical management

 

 
   
 
 
     
 

Must Read:

 
 

SAH by Robert Brown, MD
SAH in Nigeria by Biodun Ogungbo, FRCS

 
     
     
     
     
     
     
     
     
   
     
  Created by B I Ogungbo in September 2002. Modified May 2009. ©